Singles
2018 Jalisco Open
Champion	Marcelo Arévalo
Runner-up	Christopher Eubanks
Score	6–4, 5–7, 7–6(7–4)

Mirza Bašić was the defending champion but chose not to defend his title.

Marcelo Arévalo won the title after defeating Christopher Eubanks 6–4, 5–7, 7–6^(7–4) in the final.

Seeds

Draw

Finals

	Semifinals							Final
		Christopher Eubanks	6	77
		Peđa Krstin	2	65
									Christopher Eubanks	4	7	64
								6	Marcelo Arévalo	6	5	77
	6	Marcelo Arévalo	6	2
		Brayden Schnur	3	0r

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	A Menéndez Maceiras	65	6	7
		B Mousley	77	2	5			1	A Menéndez Maceiras	2	5
		D Petrović	6	7					D Petrović	6	7
	WC	T Hank	4	5												D Petrović	4	4
	WC	G López Villaseñor	1	6	65											C Eubanks	6	6
		C Eubanks	6	3	77				C Eubanks	77	78
		A Šetkić	4	2				7	V Estrella Burgos	65	66
	7	V Estrella Burgos	6	6																			C Eubanks	6	77
	3	D Novikov	63	3																			P Krstin	2	65
		P Krstin	77	6					P Krstin	6	6
	Q	J Ward	4	710	3			WC	M Sánchez	3	1
	WC	M Sánchez	6	68	6											P Krstin	6	1	6
	Alt	A Pavić	7	5	6										8	D King	2	6	2
		E Leshem	5	7	3			Alt	A Pavić	3	6	4
		R Quiroz	6	3	3			8	D King	6	2	6
	8	D King	3	6	6

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	6	M Arévalo	6	6
	Q	F Gaio	1	4				6	M Arévalo	6	6
		Christopher Heyman	4	65					A Sarkissian	3	3
		A Sarkissian	6	77											6	M Arévalo	77	3	6
		J-P Smith	6	65	6											J-P Smith	64	6	3
		DE Galán	2	77	1				J-P Smith	3	6	6
	WC	L Patiño	4	67				4	F Peliwo	6	1	2
	4	F Peliwo	6	79																		6	M Arévalo	6	2
	5	K King	6	3	3																		B Schnur	3	0r
		B Schnur	2	6	6				B Schnur	7	4	77
		S Giraldo	6	3	1r			Alt	J Hernández-Fernández	5	6	65
	Alt	J Hernández-Fernández	2	6	4											B Schnur	6	77
	Q	J Souza	6	3	5										2	M Moraing	3	64
	Q	G Escobar	2	6	7			Q	G Escobar	6	5	2
		B Zapata Miralles	1	61				2	M Moraing	2	7	6
	2	M Moraing	6	77

References

• Main Draw
• Qualifying Draw