EMD may refer to:
Finance and commerce
- Earnest money deposit, in the United States, a security deposit, especially for real estate
 
Medicine
- Electromagnetic diaphragm
 - Electromechanical dissociation
 - Emergency medical dispatcher
 - Enamel matrix derivative
 - Esophageal motility disorder
 - Merck Group, known as EMD in Canada and the United States, a German pharmaceutical company
 
Science and technology
- Electrolytic manganese dioxide
 - Emerin
 - Empirical mode decomposition
 - Equilibrium mode distribution
 - ReadyBoost, disk-caching software
 
Transport
- East Midlands Parkway railway station, in England
 - Electro-Motive Diesel, an American locomotive manufacturer
 - Electronic Miscellaneous Document in the airline industry
 - Emerald Airport, in Queensland, Australia
 
Other uses
- Schneider Electric EMD an Armenian-Serbian electric company
 - EMD (band), a Swedish band
 - Earth mover's distance
 - European Marketing Distribution, a European purchasing organization for grocery stores
 - European Maritime Day
 
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