Ione may refer to:
Places
- Ione, California, a city
 - Ione, Colorado, an unincorporated community
 - Ione, Nevada, an unincorporated community
 - Ione, Oregon, a city
 - Ione, Washington, a town
 - Ionopolis or Ione, an ancient town near Antioch
 
People
- Ione Band of Miwok Indians, a federally recognized tribe in California
 - Ione Belarra (born 1987), Spanish politician
 - Ione Christensen (born 1933), Canadian politician
 - Ione Virginia Hill Cowles (1858-1940), American clubwoman, social leader
 - Ione Wood Gibbs (c. 1871–1923), American educator, journalist, and clubwoman
 - Ione Grogan (1891–1961), American academic and educator
 - Ione Skye (born 1970), British-American actress
 
Other uses
- Tropical Storm Ione (disambiguation), one Atlantic and several Pacific Ocean hurricanes, storms and typhoons
 - Ione (plant), a genus of orchids
 - Ione (isopod), a genus of isopod in the family Bopyridae
 - Ione (mythology), one of the Nereids in Greek mythology
 
See also
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