Leo Smith may refer to:
- F. Leo Smith (1903-1999), American state legislator and district attorney
 - Leo Smith (baseball) (1859–1935), American baseball player
 - Leo Smith (composer) (1881–1952), English composer active in Canada
 - Leo Smith (sculptor) (born 1947), American sculptor
 - Leo Richard Smith (1905–1963), American prelate of the Roman Catholic Church
 - Wadada Leo Smith (born 1941), American avant-garde jazz trumpeter and composer
 - Leo Smith (hurler), Irish hurler
 - Leo W. Smith II, United States Air Force general
 
See also
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