Loy or Loys is both a given name and a surname. Notable people with the name include:
Given name:
- Loy Allen Bowlin (1909–1995), outsider artist
 - Loy Allen Jr. (born 1966), former NASCAR driver
 - Loy Hanning, Major League Baseball pitcher in 1939 and 1942
 - Loy W. Henderson (1892–1986), United States Foreign Service Officer
 - Loy Hering, (c. 1484–1564), German Renaissance sculptor
 - Loy Mendonsa, Indian film singer
 - Loy Petersen (born 1945), retired American professional basketball player
 - Loy Vaught (born 1968), retired American basketball player
 - Loy F. Weaver (born 1942), politician from Louisiana, USA
 - Loys of Gruuthuse (c. 1422–1492), better known as Lewis de Bruges, lord of Gruuthuse
 - Loys Louis Bourgeois (composer) (c. 1510–1560), French composer and music theorist of the Renaissance
 - Loÿs Delteil (1869–1927), French engraver and lithographer, publisher, dealer, and art historian
 
Surname:
- Angie Loy (born 1982), American field hockey forward
 - Brendan Loy, American blogger
 - Christof Loy (born 1962), German opera director
 - David Loy (born 1947), American Buddhist philosopher
 - Egon Loy (born 1931), German former professional football goalkeeper
 - Frank E. Loy, American diplomat and former United States Under Secretary of State for Global Affairs
 - James Loy (born 1942), United States Coast Guard admiral, former TSA administrator, former Deputy Secretary of the U.S. Department of Homeland Security
 - Joseph F. Loy (1824-1875), American politician
 - Julien Loy (born 1976), French triathlete
 - Matthias Loy (1828–1915), American Lutheran theologian
 - Mina Loy (1882–1966), British artist, poet, playwright, novelist, futurist, actor, Christian Scientist, designer of lamps and bohemian
 - Myrna Loy (1903–1993), American motion picture actress
 - Nanni Loy (1925–1995), Italian film, theatre and TV director
 - Rachel Loy, American solo artist
 - Rory Loy (born 1988), Scottish footballer
 - Tristan Loy (born 1973), French long distance and marathon speed skater and inline speed skater
 - William A. Loy (1895-1982), American politician
 - François De Loys (1892–1935), Swiss oil geologist and discoverer of "Loy's Ape"
 
See also
- Saint Loye, better known as Saint Eligius (c. 588-660)
 - the title character of "Helen O'Loy", a 1938 science fiction story by Lester del Rey
 
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