MI2, Mi2, Mi-2, M:i-2, or Mi 2 may refer to:
- MI2, the British Military Intelligence Section 2
 - Mi2 (band), a Slovenian rock band founded in Rogatec in 1995
 - Mi2 (console), a handheld game console developed and created by Dutch company Planet Interactive
 - Mil Mi-2, small, lightly armed turbine-powered transport helicopter
 - Mission: Impossible 2 (also M:i-2), a 2000 action spy film directed by John Woo
 - Square mile (also mi2), an imperial and US unit of measure for area
 - Xiaomi Mi 2, an Android smartphone
 - Monkey Island 2: LeChuck's Revenge, a 1991 video game
 
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