Mike or Michael James may refer to:
- Mickie James (born 1979), American professional wrestler
 - Mike James (American football) (born 1991), American football running back
 - Michael James, American musician with Explosions in the Sky
 - Michael James (Australian footballer) (born 1971), Australian rules footballer
 - Mike James (baseball) (born 1967), American baseball player
 - Mike James (basketball, born 1975), American basketball player
 - Mike James (basketball, born 1990), American basketball player
 - Michael James (cricketer, born 1934), English cricketer
 - Michael James (cricketer, born 1987), English cricketer
 - Michael James (politician) (1861–1943), Canadian politician of the early 20th century
 - Michael James (producer) (born 1962), American record producer, guitarist, and mixing engineer
 - Michael James (quilt artist) (born 1949), American artist
 - Michael James (writer), pseudonym of a British writer, educator and illustrator
 - Mike James (rugby union) (born 1973), Canadian rugby union player
 - Michael James (singer), British singer and songwriter
 - Michael N. G. James (born 1940), professor of biochemistry at the University of Alberta
 
See also
- All pages with titles beginning with Michael James
 - James Michael (disambiguation)
 
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