Openshaw is a ward in the City of Manchester, United Kingdom.
Openshaw may also refer to:
People with the surname
- Jennifer Openshaw, American radio personality
- Olive F. Openshaw, English illustrator; see Mary Mouse
- Peter Openshaw (judge) (born 1947), English judge
- Peter Openshaw (immunologist) (born 1954), English immunologist
- Reginald Openshaw Lawson (1880–?), English footballer
- Thomas Horrocks Openshaw (1856–1929), English surgeon
- William Openshaw (1851–1915), English rugby union international
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