Pope is a Scottish surname meaning "father".
- Albert Augustus Pope (1843–1909), American bicycle and automobile manufacturer
 - Alexander Pope (1688–1744), English poet
 - Alexander Pope (actor) (1763–1835), Irish actor and painter
 - Anson W. Pope (1812–1871), American politician
 - Arthur Upham Pope (1881–1969), American archaeologist and historian
 - Barbara S. Pope (born 1951), U.S. Department of Defense official
 - Barton C. Pope (1813–1862), Florida state representative
 - Bill Pope (born 1952), American cinematographer
 - Brent Pope (rugby analyst) (born 1962), New Zealand-born rugby analyst for Irish television
 - Carl C. Pope (1834–1911), American legislator and jurist
 - Carly Pope (born 1980), Canadian actress
 - Carole Pope (born 1950), Canadian singer
 - Cassadee Pope (born 1989), American singer
 - Charles Pope (disambiguation), several people
 - Cheryl Pope (fl. 2000s–2020s), American artist
 - Christopher Pope (physicist) (fl. 1970s–2020s), American physicist
 - Clifford H. Pope (1899–1974), American herpetologist
 - Cora Scott Pond Pope (1856–after 1932), American teacher, pageant writer, real estate developer
 - Duane Earl Pope (born 1943), American bank robber and murderer
 - Dudley Pope (1925–1997), British author
 - Dudley Pope (cricketer) (1906–1934), English cricketer
 - Eddie Pope (born 1973), American football (soccer) player
 - Edmund Mann Pope (1837–1906), American military officer and politician
 - Edwin Pope (1928–2017), American journalist
 - Eva Pope (born 1967), English actress
 - Everett P. Pope (1919–2009), US Marine Corps officer and recipient of the Medal of Honor
 - Frankie Pope (1884–1953), English association footballer
 - Fred Pope (1909–1983), Scottish association footballer
 - Generoso Pope (1891–1950), Italian-American businessman
 - Generoso Pope Jr. (1927–1988), American media mogul
 - Georgina Pope (1862–1938), Canadian military nurse
 - Gustav Pope (1831–1910), British painter
 - Hugh Pope (1869–1946), English Dominican biblical scholar
 - James Pope (disambiguation), several people
 - Jessie Pope (1868–1941), English poet
 - John Pope (disambiguation), several people
 - Kyle Pope (fl. 2010s–2020s), American editor and publisher
 - Laurence Pope (1945–2020), American diplomat
 - Lawrence Pope (1940–2013), American lawyer and legislator
 - Leonard Pope (born 1983), American football player
 - Leslie Pope (1954–2020), American set decorator
 - Lloyd Pope (born 1999), Australian cricketer
 - Lucas Pope (born 1977/78), American video game developer
 - Lynda Pope (born 1953), Australian chess player
 - Mal Pope (born 1960), Welsh musician
 - Marion Manville Pope (1859–1930), American poet, author, traveler, philanthropist
 - Mark Pope (born 1972), American basketball player
 - Martin Pope (1918–2022), American physical chemist
 - Nathaniel Pope (1784–1850), American politician and judge of Illinois
 - Nick Pope (disambiguation), several people
 - Norm Pope (1908–1985), Australian rugby league footballer
 - Odean Pope (born 1938), American tenor saxophonist
 - Ollie Pope (born 1998), English cricketer
 - Paul Pope (born 1970), American alternative cartoonist
 - Peggy Pope (1929–2020), American actress
 - Percival C. Pope (1841–1922), American Marine Corps Brevet Medal recipient
 - Roland Pope (1864–1952), Australian cricketer and ophthalmologist
 - Spencer Pope (1893–1976), American football player
 - Tim Pope (born 1956), music video director
 - Tom Pope (born 1985), English association footballer
 - Tony Pope (1947–2004), American voice actor
 - Vyvyan Pope (1891–1941), British World War II General
 - Walter Pope (1627–1714), English astronomer and writer
 - Walter Elmer Pope (1879–1944), American politician and lawyer
 - Walter Lyndon Pope (1889–1969), United States federal court judge
 
Given name
- Pope Yeatman (1861–1953), American mining engineer
 
Nickname
- Eoin O'Mahony (politician) (1905–1970), Irish barrister, genealogist, and political activist referred to as Eoin "the Pope" O'Mahony
 - Paul Castellano (1915–1985), Mafia boss frequently referred to as "The Pope"
 - Donn Pall (born 1962), American baseball player nicknamed "The Pope"
 - The Pope (wrestler) (born 1978), a ring name of Elijah Burke
 
See also
- Popé (c. 1630 – c. 1692), Pueblo leader
 - Popo (disambiguation)
 
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