RER may refer to:
Transport
In France
- Réseau Express Régional, or RER d'Île-de-France, the commuter rail service serving Paris and its suburbs
 - Réseau Express Régional Franco-Valdo-Genevois, now called Léman Express, commuter rail service serving Geneva (Switzerland), Annemasse (France) and its suburbs
 
In Belgium
- Réseau Express Régional Bruxellois (Brussels Regional Express Network), the commuter rail service serving Brussels and its suburbs and commuters
 - Réseau Express Régional Gantois (Ghent Regional Express Network), the commuter rail service serving Ghent and its suburbs and commuters
 
In Switzerland
- Réseau Express Régional Bernois, the name used for the Bern S-Bahn in French speaking areas.
 - Réseau Express Régional Vaudois, commuter rail service serving Vaud and its suburbs
 - Réseau Express Régional Fribourgeois, commuter rail service serving Fribourg and its suburbs
 - Réseau Express Régional trinational de Bâle, the name used for the Basel S-Bahn in French speaking areas.
 - Réseau Express Régional franco-valdo-genevois, now called Léman Express, commuter rail service serving Geneva, Annemasse and its suburbs
 
In Argentina
- Red de Expresos Regionales, a planned commuter rail service in Buenos Aires
 
In Canada
- GO Regional Express Rail, a planned commuter rail service in Toronto and its suburbs
 
Other uses
- Rebuilt Reading electric multiple units
 - The Real Estate Roundtable, a non-profit public policy organization that represents the interests of real estate
 - Real exchange rate, the purchasing power of a currency relative to another at current exchange rates and prices
 - RēR, the standard abbreviation for the label Recommended Records
 - Resident Evil: Revelations, a Capcom game
 - Respiratory exchange ratio, the ratio between the amount of carbon dioxide produced in metabolism and oxygen used
 - Rough endoplasmic reticulum, a type of endoplasmic reticulum protein-manufacturing ribosomes
 
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